The Swedish Research Council has granted Jin-ping Li SEK 797,320 in project grants for research on coronavirus and covid-19
Novel function of platelets in tumour blood vessels found
50 miljoner till forskning om antibiotikaresistens
Carl-Henrik Heldin, senior professor at IMBIM, has been appointed by the European Commission as chair of the committee to appoint members of the ERC Scientific Council.
European Commissioner for Innovation, Research, Culture, Education and Youth has invited six high-level scientists to identify future members of the ERC Scientific Council. One of the six is Carl-Henrik Heldin, senior prefessor at IMBIM.
Intensive hunt for drugs to fight COVID-19
The entire world is currently waiting for a vaccine against COVID-19. Intensive research is ongoing to develop useful drugs against the novel coronavirus SARS-CoV-2. At Uppsala Biomedical Centre (BMC), substances are being tested that attack the same type of enzyme as drugs against HIV and hepatitis C.
Tests provide new picture of the spread of the virus
Two recent studies testing for antibodies against the coronavirus SARS-CoV-2 provide a new picture of the spread of virus in Sweden. “To gain a more realistic picture of the spread of the virus in Sweden, we need to perform more tests,” says Åke Lundkvist, professor of virology at Uppsala University.
How gene flow between species influences the evolution of Darwin’s finches
Despite the traditional view that species do not exchange genes by hybridisation, recent studies show that gene flow between closely related species is more common than previously thought. A team of scientists from Uppsala University and Princeton University now reports how gene flow between two species of Darwin’s finches has affected their beak morphology. The study is published today in Nature Ecology and Evolution.
Kerstin Lindblad-Toh has been elected as a member to the National Academy of Sciences
Kerstin Lindblad-Toh, Professor of Comparative Genomics at Uppsala University, has been elected as one of 146 new members of the National Academy of Sciences, founded by Abraham Lincoln in 1863.
Shady Younis and Gustav Brander has received ”The Wallenberg Foundation Postdoctoral Scholarship Program at Stanford” respectively ”The Wallenberg Foundation scholarship program for postdoctoral studies at Massachusetts Institute of Technology (MIT) and Broad Institute"
New insights into evolution: why genes appear to move around
Scientists at Uppsala University have proposed an addition to the theory of evolution that can explain how and why genes move on chromosomes. The hypothesis, called the SNAP Hypothesis, is presented in the scientific journal PLOS Genetics.
Mikael Sellin appointed Future Research Leader by SSF
“Lethal” mutation makes tuberculosis bacteria resistant to antibiotic
Antibiotic-resistant tuberculosis is a common and serious problem globally. In a new article, researchers from Uppsala University describe how tuberculosis bacteria that carries a mutation that in theory should kill them manages to stay alive. The researchers discovered that the same trick that kept the bacteria alive also made them resistant to a very important type of antibiotic.
Maria Letizia Di Martino has been awarded an ESCMID Research Grant 2020
Maria Letizia Di Martino has been awarded 20,000 € by ESCMID (European Society for Clinical Microbiology and Infectious Diseases). The project - Revealing the Shigella flexneri epithelial invasome in a human enteroid infection model - will provide a global map of the Shigella virulence factors required for infection of the human “mini-intestine” model. This will form a solid basis for future molecular studies of human shigellosis, a research field thus far hampered by the lack of physiological infection models.
Carl-Henric Heldin, Staffan Johansson and Gunnar Pejler have been awarded a total of 10.6 million SEK by the Swedish Cancer Society, Cancerfonden
Cancerfonden has decided to give an additional SEK 670 million to Swedish cancer research. This means that the Swedish Cancer Society decided this year on a record dividend of SEK 770 million. It is the largest amount in the history of the Swedish Cancer Society.
Formas has decided to award Dan Andersson, Kerstin Lindblad-Toh och Linus Sandegren three million SEK each in research funds in the Annual Open Call for Research and Development Projects 2019
Linus Sandegren has been awarded the educational prize Inspiriet by the Medical Studies Council (Medicinska studierådet)
Medicinska studierådet har tilldelat Linus Sandegren, Universitetslektor vid Institutionen för medicinsk biokemi och mikrobiologi, Uppsala universitet, det pedagogiska priset Inspiriet. Kursledare, Medicinsk mikrobiologi, 8.0 hp, Läkarprogrammet.
Dan Andersson has been awarded SEK 5 million over three years by the Erling-Persson Family Foundation for the project “Rapid diagnostics to reduce antibiotic resistance and the adverse effects of antibiotics”.
High levels of hyaluronan polysaccharide in serum from patients infected with dengue virus predict severe disease and contribute to increased blood vessel leakage
Dengue virus infection is transmitted by mosquitoes and is increasing rapidly in the world due to global warming and travel abroad. The infection causes suffering, consumes medical care resources, and can sometimes develop into a deadly disease that, among other things. manifests itself in a greatly increased leakage in the blood vessels that leads to fluid loss. There is no effective dengue virus vaccine and no specific treatment for patients with dengue fever.
Bacterial Persisters Promote the Spread of Antibiotic Resistance Plasmids in the Gut
Antibiotic therapy of bacterial infections may fail either because the microbe becomes genetically resistant to the administered drug, or because it enters a slow growing antibiotic-tolerant state – a phenomenon known as ”persistence”.
How the herring adapted to the light environment in the Baltic Sea
The evolutionary process that occurs when a species colonizes a new environment provides an opportunity to explore the mechanisms underlying genetic adaptation,which is essential knowledge for understanding evolution and the maintenance of biodiversity. An international team of scientists, led by researchers from Uppsala University, Uppsala, Sweden, reports that a single amino acid change in the light-sensing rhodopsin protein played a critical role when herring adapted to the red-shifted light environment in the Baltic Sea. Remarkably about one third of all fish living in brackish or freshwater carry the same change. The study is published today in PNAS.
Anahita Hamidi is rewarded by the Swedish Society for Medical Research, with one of the country's most sought after scholarships for young, extra promising researchers.
The scholarships are awarded by SSMF with SEK 850,000 for two years of full-time research and SEK 658,000 for two years at half-time. In total, SSMF will support young medical researchers in 2019 with over SEK 70 million. The 26 fellows come from four different universities.
Birgitta Tomkinson has been awarded STINT's "Grants for Teaching Sabbaticals"
Kerstin Lindblad-Toh becomes honorary doctor at SLU
Kerstin Lindblad-Toh har utsetts till veterinärmedicine hedersdoktor vid Sveriges Lantbruksuniversitets (SLU:s) fakultet för veterinärmedicin och husdjursvetenskap. Totalt har sju nya hedersdoktorer utsetts, som promoveras den 5 oktober i Uppsala.
Omenn Prize goes to Roderich Römhild for his article on Preventing Antibiotic Resistance
The $5,000 Omenn Prize for the best article published in the previous calendar year in any scientific journal on a topic related to evolution in the context of medicine and public health goes to Roderich Römhild for his paper: Roemhild, R., Gokhale, C. S., Dirksen, P., Blake, C., Rosenstiel, P., Traulsen, A., … Schulenburg, H. (2018). Cellular hysteresis as a principle to maximize the efficacy of antibiotic therapy. Proceedings of the National Academy of Sciences, 115(39), 9767–9772. doi:10.1073/pnas.1810004115
New genes out of random gene sequences
One key question in evolutionary biology is how novel genes arise and develop. Swedish researchers now show how new genes and functions that are advantageous to bacteria can be selected from random DNA sequences. The results are presented in the scientific journal mBio.
Helen Wang has received SEK 200,000 from the Foundation Clas Groschinsky's Memorial Fund
Fan Han (Leif Andersson research group) has received a prestigious award from the Chinese government to PhD students abroad. Fan will be one of nine Chinese students in Sweden that get this award this year
Dan Andersson is awarded 18 million by the Wallenberg Foundations in the form of a five-year grant for free research
Twenty-two Excellent Researchers Chosen to be Wallenberg Scholars
The researchers – among the foremost in their field in Sweden – receive SEK 18 million each from the Wallenberg Foundations in the form of a five-year grant for free research.
Jumping genes, antibiotics resistance, new therapies for infections, diabetes and Parkinson’s disease, secure technology for wireless communication, self-repairing batteries, a better understanding of climate change, and searching for Earth-like planets are examples of the research that will be conducted by some of the twenty-two Wallenberg Scholars.
Svårdetekterad antibiotikaresistens underskattat kliniskt problem
I de flesta fall när en bakterie behandlas med antibiotika som den är känslig emot så fungerar behandlingen. Men ibland fungerar inte det valda antibiotikat och en av förklaringarna till detta är heteroresistens, ett fenomen som forskare vid Uppsala universitet tillsammans med kollegor vid Emory University i USA klarlagt i detalj i en ny studie.
Gunnar Pejler receives the largest project grant from Hjärt och Lungfonden, a total of SEK 2.4 million over three years. He is one of the world's leading experts on mast cells, a type of white blood cell that has a key role in asthmatic reactions.
The Linnaeus Medal is awarded to Professor Leif Andersson, the medal is awarded at the Winter Promotion on January 25
Jenny Hesson has been awarded 633 000 SEK in research funding from the Carl Trygger Foundation
Andreas Wallberg has been awarded SciLifeLab Bioinformatics Long-term Support (WABI) by the National Bioinformatics Infrastructure Sweden at SciLifeLab for his project 'Environmental genomics in the Northern krill'
Helen Wang has been awarded 306 000 SEK in research funding from the Carl Trygger Foundation
Formas has decided to award Patric Jern three million SEK in research funds in the Annual Open Call for Research and Development Projects 2018
Göran Akusjärvi, Ingvar Ferby, Paraskevi Heldin, Per Jemth, Jin-ping Li, Kohei Miyazono och Aristidis Moustakas have been awarded a total of 17.6 million SEK by Cancerfonden
Det är Johanna Lindahl, forskare inom veterinär-epidemiologi, som får priset och 100 000 kronor från Swedish Institute for Global Health Transformation, SIGHT. Priset delas ut för en utmärkt vetenskaplig insats inom global hälsa.
Antibiotikaresistens och interaktionen människa och djur i fokus för SIGHT Award 2018
Andreas Wallberg and Mathew Webster have been awarded a total of SEK 7 million of Research project grants by VR.
Birgitta Heyman, Patric Jern, Jin-ping Li, Åke Lundkvist, Aristidis Moustakas, Mikael Sellin and Helen Wang have been awarded a total of SEK 31 million of Starting- and Research project grants by VR.
Details of protein evoltuion investigated
Proteins govern the biology of the cell. Through random mutation the sequences of our proteins slowly change over time, usually without affecting function. But sometimes new functions will be invented in this process. Scientists at Uppsala University have studied such a case in molecular detas. The results show how several factors conspire to shape a plastic protein-protein interaction.
New knowledge about retrovirus-host coevolution
Retroviruses have colonised vertebrate hosts for millions of years by inserting their genes into host genomes, enabling their inheritance through generations as endogenous retroviruses (ERVs). Researchers from Uppsala University now provide new knowledge about the long-term associations of retroviruses and their hosts by studying ERV variation and segregation in wild and domestic rabbit populations. The findings are being published in Proceedings of the National Academy of Sciences (PNAS).
Ny metod kan bromsa antibiotikaresistens
Tyska och svenska forskare visar i en ny studie hur man genom att snabbt växla mellan två olika antibiotika drastiskt kan öka deras förmåga att döda bakterier samt bromsa resistensutvecklingen. Resultaten publiceras i den vetenskapliga tidskriften PNAS.
Kaninens tama beteende associerat med tydliga förändringar i hjärnans utveckling
En internationell forskargrupp har använt högupplösande magnetkamera (MRI) för att undersöka hur domesticeringen har påverkat hjärnans utveckling hos tamkaninen. Resultaten visar på tydliga skillnader mellan vilda och tama kaniner, i synnerhet i de regioner av hjärnan som kontrollerar rädsla. Studien publiceras i den amerikanska vetenskapsakademins tidskrift PNAS.
New research shows that bacteriophages (viruses that infect bacteria) can contribute to new functions by revealing hidden potential in their bacterial hosts.
Virus genes from city pond rescue bacteria
Mikael Sellin is awarded with The Lennart Philipson Award 2018
New research from Uppsala University shows that even low concentrations of antibiotics can lead to the development of high antibiotic resistance in bacteria.
Antibiotics resistant antibiotics are a global and growing problem in health care. In order to avoid further resistance development, it is important to understand where and how antibiotic resistance in bacteria occurs.
The European Research Council (ERC) has allocated a total of € 653 million in grants for the announcement of the 2017 ERC Advanced Grants. Uppsala University receives a contribution in life sciences. This grant goes to Carl-Henrik Heldin, cancer researcher at IMBIM.
Gerli Rosengren Pielberg has been appointed as a lecturer in genomics.
A new study shows that there has been a larger gene flow than previously thought among elephant species, both living and extinct. In addition, it points out that African savannah elephants and forest elephants should be seen as two different species.
Philosophy doctor Simon Forsberg has been awarded by The Royal Swedish Academy of Agriculture and Forestry